Cellular and molecular mechanisms of asbestos carcinogenicity: implications for biopersistence.
نویسندگان
چکیده
منابع مشابه
Cellular and molecular mechanisms of asbestos carcinogenicity: implications for biopersistence.
Carcinogenic agents can influence the carcinogenic process either by mutating critical target genes or by increasing the number of cells at risk for mutations. Cytogenetic and molecular studies of asbestos-related cancers indicate that inactivation or loss of multiple tumor suppressor genes occurs during lung cancer development. Aneuploidy and other chromosomal changes induced by asbestos fiber...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1994
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.94102s519